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Pathology gallery 3

Caeseating necrosis due Mycobacterium tuberculosis infection

This slide shows the typical appearances of caeseating necrosis seen in Mycobacterium tuberculosis infection.  The central area of necrosis is surround by an inflammatory infiltrate containing lymphocytes, epitheloid macrophages and multinucleate giant cells.  Spread and confluence of these proliferative granulomatous lesions are the basic mechanism in active progressive tuberculosis.


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